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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59bec59a21dbd0334f8e5d32aa3e955302e1c1fd0288dbffe92a9386dfb29f2e' 
  AND token = 'eOx8s81+0KSF8s4QNmuiVl29jsJe0j9s5ka7yt8xMzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}